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About the Surgery.

Advanced Microsurgical Technique

Deep Cervical Lymphaticovenous Anastomosis (LVA) is an avant-garde surgical methodology conceived by Professor Qingping Xie of Hangzhou Qiushi Hospital. Its pioneering objective is the establishment of a tangible conduit that expedites the removal of toxic proteins, effectively expelling protein accumulations from the brain. The breakthrough point for his method is the fact that the surgical site is on the side of the neck area which is extracranial (outside skull), which provides a significant control over the safety of the procedure and is considered a much less invasive method. According to the anatomy of the lymphatic’s distribution, the first exit of brain lymphatic vessel happens at V subdivision on the neck.

Technique of LVA surgery visualizedTechnique of LVA surgery visualized

Technique of LVA surgery visualized

The impairment of this circulation system might lead to the accumulation of substances like tau proteins within brain tissue regions. The neurotoxicity of these proteins can cause synaptic damage and neuronal cell death, contributing to the onset of Alzheimer's disease.

State-of-the-art microsurgical equipment to be used in LVA procedures in the near future

State-of-the-art microsurgical equipment to be used in LVA procedures in the near future

Using state of the art microsurgical techniques, we create precise connections between lymphatic vessels and veins in the deep cervical region. This innovative procedure helps improve cerebral fluid drainage and has shown promising results in slowing AD progression. To do this, we will use precise machine-controlled microsurgical instruments and a microscope to perform the surgery in the near future.

Prof Qingping Xie's illustration and vision on brain lymphedema for AD patients:

1.

Proven Efficacy: LVA, a time-tested surgical technique, has garnered global acclaim for its unparalleled effectiveness in mitigating lymphedema within the limbs. It has unequivocally demonstrated its safety and efficacy over two decades.

2.

Safety Profile: Despite the pioneering nature of Professor Xie's method, it has been rigorously validated as intrinsically safe, with no recorded post-operative adversities.

3.

Standardization Potential: LVA holds the potential for standardization, possibly benefiting from AI-assisted training mechanisms, thereby facilitating scalability.

4.

Patient Comfort: The extracranial nature of the procedure, with an average operation duration of approximately four hours, ensures optimal patient comfort and a relatively abbreviated hospital stay.

5.

Immediate Results: Patients typically experience rapid improvements in cognitive and motor functions shortly following the procedure, with sustained enhancements throughout the follow-up period due to the nature of Lymphatic reconstruction surgery.

6.

Permanent assistance on Brain's lymphatic environment: LVA surgery affords a one-time, permanent amelioration in patients' conditions by establishing a tangible pathway for protein drainage.

Patient-Centered Care

Dedicated medical team providing personalized patient care

Dedicated medical team providing personalized patient care

At Hangzhou Qiushi Hospital, every patient receives individualized treatment plans based on their specific condition and MMSE scores. Our multidisciplinary team works closely with patients and their families throughout the entire treatment journey, from initial consultation through post-operative care and rehabilitation. We believe in transparent communication and comprehensive support.

White Glove Service

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We offer a comprehensive range of services to meet your needs. Our team is dedicated to providing the highest quality care and support to our patients. They have been trained to to support tLVA surgery and after surgery care for more than 5 years. We recommend you stay in the hospital for 14 days after the surgery. We also have a 24/7 English translator on site. Explore the living and hospital areas virtually below!

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Living Area

Located in the beautiful city of Hangzhou, we offer a comfortable and convenient living area for our patients. Explore the living areas virtually below!

Explore the hospital area virtually below!

Recovery and Outcomes

Patient recovery process and rehabilitation activities

Patient recovery process and rehabilitation activities

Post-operative recovery focuses on cognitive rehabilitation and monitoring treatment effectiveness. Our patients typically experience improved cognitive function and quality of life. The minimally invasive nature of the LVA procedure allows for faster recovery times compared to traditional brain surgeries, with most patients able to return to normal activities within weeks.

Brain Region Analysis Results

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The left chart is the amyloid reduction after DC-LVA after 3 months. The right cart shows the CAT scan results before and 3 months after surgery. These promising results fuels our research and confidence in the procedure. Additionally, check out other stories from our patients.

Video Explainer in Chinese.

For English translation, contact us for more documents and schedule a Zoom call.

Eligibility Chart.

Scroll right to see all columns
AD stagesMildModerateSevereEligibility for AD-LVA Surgery
Life expectancy >5 yearsYesYesYesOK to proceed
Life expectancy <5 yearsNoNoNoNot eligible
No major blood thinning disease such as leukemiaYesYesYesOK to proceed
Have major blood thinning disease such as leukemiaNoNoNoNot eligible
Able to travel long distance without respiratory diseasesYesYesYesOK to proceed
Not able to travel long distance without respiratory diseasesNoNoNoNot eligible
Fine with minor scars on both neck (4-6cm incision)YesYesYesOK to proceed
Not fine with major scars on both neck (4-6cm incision)NoNoNoNot eligible

Pricing.

Early stage AD

23<MMSE

35,000 USD

Expected LVAs:

Approx. 10-15 LVAs bilaterally

Middle stage AD

10<MMSE<22

40,000 USD

Expected LVAs:

Approx. 15-20 LVAs bilaterally

Late stage AD

MMSE<10

45,000 USD

Expected LVAs:

Approx. 25+ LVAs bilaterally

*All prices are estimates. Final pricing may vary based on individual assessment and requirements.

Fee Structure.

The surgery for international patients:

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40K USD for the whole LVA surgery and up to two weeks of hospitalization. The LVA surgery will normally perform in total of 15-20 lymphatic-vein anastomosis on both side of the neck.

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50% deposit needed to wire transfer/direct deposit to designated hospital account, invoice and letter of hospitalization will be issued upon receipt of the payment for Visa purposes. A scheduled surgery time can be established at that time (Please book ahead for at least 2 weeks).

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Local vehicle transportation for inbound flights from Shanghai airport to Hangzhou Qiushi Hospital is included in the price. Please note we can only pick up from either Shanghai (PVG) Pudong airport or from Hangzhou Xiaoshan International Airport (HHG).

Contact.

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The AD-LVA Surgery